abstract：BACKGROUND:This study analyzes trends in hospitalization and outcome for adult, elderly, and pediatric trauma victims in the Florida Trauma System (FTS) from 1991 to 2003, during which time the number of centers nearly doubled from 11 to 20. METHODS:Administrative data was queried for all admissions with at least one ...

journal_title：Surgery

authors： Pracht EE,Langland-Orban B,Tepas JJ 3rd,Celso BG,Flint L

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The surgical success rate of parathyroidectomy is 95%. However, in rare patients, ectopic hyperfunctioning parathyroid glands may be located in the thyroid but missed on imaging studies or during surgery. The aim of the present study was to evaluate the perioperative findings in 6 patients with intrathyroid ...

journal_title：Surgery

authors： Bahar G,Feinmesser R,Joshua BZ,Shpitzer T,Morgenstein S,Popovtzer A,Shvero J

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The prognostic significance of the leukocyte subsets in peripheral blood has not yet been investigated in hepatocellular carcinoma patients. We sought to clarify the prognostic value of preoperative peripheral blood leukocyte subset counts, especially the absolute monocyte count, in HCC patients who have und...

journal_title：Surgery

authors： Sasaki A,Iwashita Y,Shibata K,Matsumoto T,Ohta M,Kitano S

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The Hedgehog (Hh) gene family is known to regulate development of stem cells. In addition, activation is responsible for the induction of GLI1 proto-oncogene and subsequent cellular proliferation. Sonic Hedgehog (SHh), one of the Hh family members promotes carcinogenesis in airway and pancreatic epithelia, i...

journal_title：Surgery

authors： Douard R,Moutereau S,Pernet P,Chimingqi M,Allory Y,Manivet P,Conti M,Vaubourdolle M,Cugnenc PH,Loric S

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Studies of risk factors after pancreatoduodenectomy are few: some concern restricted populations and others are based on administrative data. METHODS:Multicenter clinical data were collected for 300 patients undergoing pancreatoduodenectomy to determine (by univariate and multivariate analysis) preoperative...

journal_title：Surgery

authors： Muscari F,Suc B,Kirzin S,Hay JM,Fourtanier G,Fingerhut A,Sastre B,Chipponi J,Fagniez PL,Radovanovic A,French Associations for Surgical Research.

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:An understanding of the regeneration power and operative risk of steatotic livers after hepatectomy is still unclear. We evaluated the volume regeneration and outcome of steatotic livers after donor hepatectomy. METHODS:Fifty-four, consecutive living liver donors from September 2002 to December 2003 were ev...

journal_title：Surgery

authors： Cho JY,Suh KS,Kwon CH,Yi NJ,Lee KU

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Vocal cord paralysis is associated with extrathyroidal invasive malignancy. This study was performed to analyze the presentation of patients with invasive thyroid malignancy and to determine the preoperative symptomatic and radiographic correlates of vocal cord paralysis. METHODS:In a group of 365 consecuti...

journal_title：Surgery

authors： Randolph GW,Kamani D

更新日期：2006-03-01 00:00:00

abstract：HYPOTHESIS:If (1) 3-hydroxy-3-methylglutaryl-coenzyme reductase inhibitors (statins) block the rate-limiting step in cholesterol synthesis and promote the expression of low-density lipoprotein receptors, (2) "Gram-negative sepsis" results from an abundant systemic response to bacterial lipopolysaccharide (endotoxin), (...

journal_title：Surgery

authors： Spitzer AL,Harris HW

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:It has been shown that vagal nerve stimulation (VNS) can affect body mass. The aim of this study was to evaluate effect of VNS on body mass, body composition, metabolic rate, and plasma leptin and IGF-I levels. METHODS:Eight female pigs were included in the study. Under general anesthesia, a bipolar electro...

journal_title：Surgery

authors： Sobocki J,Fourtanier G,Estany J,Otal P

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Thermal ablation by radiofrequency or laser is used increasingly for the treatment of colorectal liver metastases. Recurrence after thermal ablation is common and occurs both locally and at distant sites. One possible cause of this recurrence may be a result of growth stimulation of micrometastases in the re...

journal_title：Surgery

authors： Nikfarjam M,Muralidharan V,Christophi C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Persistent elevation of serum parathyroid hormone (PTH), despite normocalcemia, occurs in 8% to 40% of patients after parathyroidectomy. Explanations have included hypocalcemia owing to vitamin D deficiency or bone remineralization, and persistent hyperparathyroidism. METHODS:A retrospective chart review of...

journal_title：Surgery

authors： Wang TS,Ostrower ST,Heller KS

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Thyroid nodules are common; fine-needle aspirations commonly are read as indeterminate, necessitating surgery to exclude carcinoma. We developed a 6-gene array-based predictor model to diagnose benign versus malignant thyroid lesions. In this study, we verified whether quantitative reverse transcription-poly...

journal_title：Surgery

authors： Rosen J,He M,Umbricht C,Alexander HR,Dackiw AP,Zeiger MA,Libutti SK

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Carcinoid tumors of the duodenum are rare, and their natural history has not been defined. Consequently, there is no consensus on the optimal extent of surgical treatment. METHODS:The authors reviewed the records of all patients with primary carcinoid tumors of the duodenum treated at their institution from...

journal_title：Surgery

authors： Mullen JT,Wang H,Yao JC,Lee JH,Perrier ND,Pisters PW,Lee JE,Evans DB

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to review and discuss our observations on 33 patients who underwent surgical treatment for Caroli's disease (CD), focusing on diagnosis, current surgical management, and long-term outcome. METHODS:Between May 1993 and June 2004, 642 liver resections and 286 liver transplantations i...

journal_title：Surgery

authors： Kassahun WT,Kahn T,Wittekind C,Mössner J,Caca K,Hauss J,Lamesch P

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:The glial cell line-derived neurotrophic factor (GDNF) is a member of neurotrophic polypeptide family, which promotes survival and rescue of various neural cells in the central and peripheral nerve systems. We previously reported that GDNF promotes tumor cell invasion in pancreatic cancer cell lines. The pur...

journal_title：Surgery

authors： Ito Y,Okada Y,Sato M,Sawai H,Funahashi H,Murase T,Hayakawa T,Manabe T

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Laparoscopic techniques are being used increasingly in the repair of ventral hernias and offer the potential benefits of a shorter hospital stay, decreased wound complications, and possibly a lower recurrence rate. Despite good results from high-volume centers, significant complications may occur with this a...

journal_title：Surgery

authors： Perrone JM,Soper NJ,Eagon JC,Klingensmith ME,Aft RL,Frisella MM,Brunt LM

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:To compare operative morbidity, mortality, quality of life, and survival after pancreatoduodenectomy (PD) versus pancreatoduodenectomy with extended lymphadenectomy (PD/ELND) in patients with resectable pancreatic cancer. METHODS:From May 1997 to July 2003 there were 132 patients with biopsy examination-pro...

journal_title：Surgery

authors： Farnell MB,Pearson RK,Sarr MG,DiMagno EP,Burgart LJ,Dahl TR,Foster N,Sargent DJ,Pancreas Cancer Working Group.

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Lysophosphatidylcholine (LysoPC) is a product of phosphatidylcholine hydrolysis by phospholipase A2, which is associated with atherosclerosis. However, the underlying molecular mechanisms are still unclear. The purpose of this study was to determine the effects of LysoPC on monolayer permeability of human co...

journal_title：Surgery

authors： Yan S,Chai H,Wang H,Yang H,Nan B,Yao Q,Chen C

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:These experiments were designed to quantitatively compare the patterns of tissue thrombosis, cytokine response, and tissue viability in a murine model of partial (PI) versus complete hindlimb ischemia (CI), alone or with reperfusion (RE). METHODS:The control tension tourniquet was used to establish either P...

journal_title：Surgery

authors： Conrad MF,Stone DH,Albadawi H,Hua HT,Entabi F,Stoner MC,Watkins MT

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Survivin is a member of the inhibitor of apoptosis protein family, which inhibits apoptosis and regulates cell division. Survivin is expressed by the majority of human cancers, including pancreatic adenocarcinoma. We have reported that its expression is correlated with shorter survival of pancreatic cancer p...

journal_title：Surgery

authors： Kami K,Doi R,Koizumi M,Toyoda E,Mori T,Ito D,Kawaguchi Y,Fujimoto K,Wada M,Miyatake S,Imamura M

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Preconditioning is injury-induced protection against subsequent injury and may be induced by a variety of stimuli. Both males and females may be preconditioned; however, if females are relatively protected against the initial insult, is their preconditioning threshold higher? We hypothesized that preconditio...

journal_title：Surgery

authors： Pitcher JM,Tsai BM,Wang M,Kher A,Brown JW,Meldrum DR

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Antigen injected subcutaneously (SQ) results in a strong systemic immune response, whereas antigen infused orally or by the portal vein tends to induce tolerance. Nontransgenic C57BL/6J (H-2(b)), or B6, mice and transgenic 2C mice (that express a cytotoxic T cell receptor against major histocompatibility com...

journal_title：Surgery

authors： Margenthaler JA,Flye MW

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Mortality after acute respiratory distress syndrome is higher in males than in females. Gender differences in pulmonary vascular reactivity and local inflammatory response may explain this disparity. We hypothesized that endothelium-dependent pulmonary vasorelaxation is impaired in males and that this effect...

journal_title：Surgery

authors： Tsai BM,Wang M,Pitcher JM,Kher A,Brown JW,Meldrum DR

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Despite the emphasis on medical error as a major cause of hospital morbidity and mortality, there has been little published work on errors committed by trainees. This issue is particularly relevant to the training of surgeons and was addressed by our study. METHODS:Sixty simulated laparoscopic cholecystecto...

journal_title：Surgery

authors： Tang B,Hanna GB,Cuschieri A

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to clarify whether the types of portal vein (PV) occlusion during hepatectomy affect the long-term outcome in patients with hepatocellular carcinoma (HCC). METHODS:Eighty-six patients who had undergone curative hepatic resection for HCC were divided on the basis of the type of PV o...

journal_title：Surgery

authors： Makino I,Chijiiwa K,Kondo K,Ohuchida J,Kai M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine if systemic acidosis induced by peritoneal absorption of carbon dioxide (CO2 ) during laparoscopy plays a role in CO2 pneumoperitoneum-mediated attenuation of the acute phase inflammatory response associated with perioperative sepsis. The influence of hepatic polymo...

journal_title：Surgery

authors： Hanly EJ,Bachman SL,Marohn MR,Boden JH,Herring AE,De Maio A,Talamini MA

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Surgery for pancreatic necrosis is associated with a high morbidity and mortality. The aim of this study was to review the incidence of early and late complications after pancreatic necrosectomy in a large contemporary series of patients. METHODS:The clinical outcomes of 88 patients who underwent pancreatic...

journal_title：Surgery

authors： Connor S,Alexakis N,Raraty MG,Ghaneh P,Evans J,Hughes M,Garvey CJ,Sutton R,Neoptolemos JP

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The prevalence of insomnia in patients with symptomatic secondary hyperparathyroidism and the improvements of sleep disturbances after parathyroidectomy have not been previously reported. METHODS:Thirty-one patients who had undergone successful total parathyroidectomy and autotransplantation for symptomatic...

journal_title：Surgery

authors： Chou FF,Lee CH,Chen JB,Huang SC,Lee CT

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the risk of recurrent laryngeal nerve palsy (RLNP) after thyroidectomy with routine identification of the recurrent laryngeal nerve (RLN) during the operation. METHODS:The present study was confined to 521 patients, 348 total lobectomies and 178 total thyroidectomies, tre...

journal_title：Surgery

authors： Chiang FY,Wang LF,Huang YF,Lee KW,Kuo WR

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The liver is a source of systemic proinflammatory mediators in acute pancreatitis. We have investigated the effects of blood from the pancreas and intestine in liver activation and lung inflammation during early stages of experimental acute pancreatitis in a rat model. METHODS:A portosystemic shunt and a me...

journal_title：Surgery

authors： Hoyos S,Granell S,Heredia N,Bulbena O,Closa D,Fernández-Cruz L

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Surgical management of patients with metastatic or recurrent rectal cancer remains controversial. Self-expanding metal stents are increasingly used for palliative treatment of advanced tumors, although long-term results are not yet available. METHODS:Between 1996 and 2003, 521 patients underwent surgery for...

journal_title：Surgery

authors： Hünerbein M,Krause M,Moesta KT,Rau B,Schlag PM

更新日期：2005-01-01 00:00:00

abstract：:Background Insulin-like growth factor 1 (IGF-1) is an autocrine regulator of carcinoid tumors. Blockade of IGF-1 signaling has been proposed as a therapeutic target in the treatment of patients with carcinoid syndrome. We hypothesized that the induction of parallel raf-1/MEK1 pathways will block IGF-1-mediated chromog...

journal_title：Surgery

authors： Van Gompel JJ,Chen H

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the effect of adrenal venous sampling (AVS) on the management of patients with primary aldosteronism. METHODS:From September 1990 through October 2003, 203 patients with primary aldosteronism (mean age, 53 years; range, 17-80; 163 men) were selected prospectively for A...

journal_title：Surgery

authors： Young WF,Stanson AW,Thompson GB,Grant CS,Farley DR,van Heerden JA

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Intraoperative parathyroid hormone (IOPTH) monitoring in parathyroidectomy for multigland disease is less clear than for single-gland disease. This study assesses the role of IOPTH for hyperplasia. METHODS:A prospective database revealed 45 patients with hyperplasia undergoing parathyroidectomy utilizing IO...

journal_title：Surgery

authors： Weber KJ,Misra S,Lee JK,Wilhelm SW,DeCresce R,Prinz RA

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The risk of dying from primary hyperparathyroidism (pHPT) is controversial and has been explored mainly in single parathyroid gland disease. The present study investigates mortality in pHPT due to multiple parathyroid gland disease. METHODS:We used the nationwide Swedish In-patient Register and Cause-of-Dea...

journal_title：Surgery

authors： Nilsson IL,Wadsten C,Brandt L,Rastad J,Ekbom A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Recent interest in cyst fluid analysis (CFA) for carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA), and the introduction of laparoscopic surgery (LS) in the management of hepatic cysts have resulted in sporadic reports of elevated CA 19-9 and CEA levels in intrahepatic biliary cystadenom...

journal_title：Surgery

authors： Koffron A,Rao S,Ferrario M,Abecassis M

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Pelvic ring fractures (PRFs) are a major cause of morbidity and mortality in motor vehicle collisions (MVCs). Understanding the factors leading to PRFs may help improve vehicle design and safety. This study sought to determine the vehicular, crash, and occupant characteristics that contribute to PRFs. METHO...

journal_title：Surgery

authors： Rowe SA,Sochor MS,Staples KS,Wahl WL,Wang SC

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a continuous wound infusion of bupivacaine to those who receive an infusion of saline. METHODS:A prospective, randomized, blinded, placebo-controlled trial was ...

journal_title：Surgery

authors： Schurr MJ,Gordon DB,Pellino TA,Scanlon TA

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Although the effect of preoperative biliary drainage in patients with obstructive jaundice is controversial, bacterial or endotoxin translocation is one of the main postoperative problem in jaundiced patients. Failure in gut barrier functions causes bacterial translocation; homing and distribution of T lymph...

journal_title：Surgery

authors： Sano T,Ajiki T,Takeyama Y,Kuroda Y

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The objectives of the present study are to determine the long-term changes in glucose tolerance function after pancreaticoduodenectomy and to compare the effects of pancreaticojejunostomy (PJ) and pancreaticogastrostomy (PG). Patients and methods The present study consisted of 51 patients who received a panc...

journal_title：Surgery

authors： Ishikawa O,Ohigashi H,Eguchi H,Yokoyama S,Yamada T,Takachi K,Miyashiro I,Murata K,Doki Y,Sasaki Y,Imaoka S

更新日期：2004-09-01 00:00:00